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Can postural OSA be usefully identified from its severity alone?

Aihem JoharChris D TurnbullJohn R Stradling
Published in: BMJ open respiratory research (2017)
An ODI ≥40, compared with <40, halved the likelihood of POSA from 68% to 35%. Although there is clearly a relationship between overall ODI and POSA, it is not strong enough to diagnose an individual with POSA. However the relationship provides a useful way to prescreen trial subjects to enrich for POSA.
Keyphrases
  • obstructive sleep apnea
  • clinical trial
  • study protocol
  • phase iii
  • open label