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IFN-λ4 genetic variants influence clinical malaria episodes in a cohort of Kenyan children.

Gabriela Samayoa-ReyesConner JacksonSidney OgollaKatherine SabourinAdeola ObajemuArlene E DentLudmilla Prokunina-OlssonRosemary Rochford
Published in: Malaria journal (2021)
The results suggest that the ability to produce IFN-λ4 negatively affects host immune protection against P. falciparum malaria in Kenyan children.
Keyphrases
  • young adults
  • immune response
  • plasmodium falciparum
  • dendritic cells