Female genital tract host factors and tenofovir and lamivudine active metabolites.
Alyssa M LantzFlavia Kiweewa MatovuReilly JohnsonEsther IsingelRita NakalegaSamuel KabwiguMags E BeksinskaMelanie R NicolPublished in: The Journal of infectious diseases (2024)
TFVdp concentrations in cervix appear to be influenced by local inflammation. In contrast, 3TCtp FGT exposure was not affected by genital inflammation or DMETS. CuIUD users have more immune cells present, which may in turn influence local TFVdp disposition.