Drug-Induced Urinary Stone of Atazanavir Incidentally Found in an Asymptomatic Patient: A Case Report.
Maëlle PlaweckiMarie BistoquetPierre-Edouard GrilletNicolas AbdoJean-Sébastien SouweineJean-Paul CristolPublished in: Case reports in urology (2023)
A HIV-infected female treated with a combination of emtricitabine/elvitegravir/tenofovir since 2017 presented an acute renal failure during her hospitalization for a SARS-CoV2 pneumonia. A computed tomography demonstrated left ureterohydronephrosis and ureteral stone. Fragments extracted by ureteroscopy showed a calculus composed of atazanavir and calcium oxalate. The patient's medical history showed atazanavir intake during ten years and then discontinued in 2017. This case report emphasizes that drug-induced urolithiasis should be considered when renal function declines, even far from discontinuation of atazanavir and without clinical signs of renal colitis. Moreover, identification of risk factors should alert to the possibility of drug-induced nephrolithiasis.
Keyphrases
- drug induced
- liver injury
- case report
- hiv infected patients
- antiretroviral therapy
- hiv infected
- sars cov
- computed tomography
- risk factors
- human immunodeficiency virus
- healthcare
- adverse drug
- magnetic resonance imaging
- editorial comment
- weight gain
- respiratory syndrome coronavirus
- intensive care unit
- weight loss
- dual energy
- electronic health record
- hepatitis c virus