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Diagnostic accuracy of two commercial SARS-CoV-2 antigen-detecting rapid tests at the point of care in community-based testing centers.

Alice BergerMarie Therese Ngo NsogaFrancisco Javier Perez-RodriguezYasmine Abi AadPascale Sattonnet-RocheAngèle Gayet-AgeronCyril JaksicGiulia TorrianiErik BoehmIlona KronigJilian A SacksMargaretha de VosFrédérique Jacquerioz BauschFrançois ChappuisAdriana RenzoniLaurent KaiserManuel SchiblerIsabella Eckerle
Published in: PloS one (2021)
We provide an independent validation of two widely available commercial Ag-RDTs, both meeting WHO criteria of ≥80% sensitivity and ≥97% specificity. Although less sensitive than RT-PCR, these assays could be beneficial due to their rapid results, ease of use, and independence from existing laboratory structures. Testing criteria focusing on patients with typical symptoms in their early symptomatic period onset could further increase diagnostic value.
Keyphrases
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