Understanding the killer-cell immunoglobulin like receptor polymorphism in retinoblastoma.

Ritu AggarwalMadhulika SharmaUsha SinghKay PoultonTanvi BhatiaNavdeep MangatNandita KakkarDeepak Bansal

Published in: Ophthalmic genetics (2023)

It is the pioneer study to report the association of killer cell immunoglobulin-like receptors in retinoblastoma. KIR2DS4*FUL and KIR2DS5 had a susceptible, and KIR3DS1/HLA-BW4 had a protective role in retinoblastoma. The results will aid in exploring the therapeutic potential of NK cell-based therapy for retinoblastoma.

Keyphrases

single cell
cell therapy
nk cells
stem cells