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Genetic and environmental causes of variation in an automated breast cancer risk factor based on mammographic textures.

Zhoufeng YeGillian S DiteTuong Linh NguyenRobert J MacInnisDaniel Francis SchmidtEnes MakalicOsamah M Al-QershiTu Nguyen-DumontBenjamin GoudeyJennifer StoneJames G DowtyGraham G GilesMelissa C SoutheyJohn L HopperSherly X Li
Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)
Early-life factors shared more by MZ pairs than DZ/non-twin sister pairs, could play a role in the variation in Cirrus, consistent with early life being recognised as a critical window of vulnerability to breast carcinogens.
Keyphrases
  • early life
  • risk factors
  • climate change
  • genome wide
  • copy number
  • gene expression