Involvement of miRNAs in cellular responses to radiation.

Joanna Rzeszowska-WolnyDorota HudyKrzysztof BiernackiSylwia CiesielskaRoman Jaksik

Published in: International journal of radiation biology (2022)

Currently, the responses of cells to ionizing radiation are mainly ascribed to changes in their redox conditions and increased intracellular levels of ROS, but the experiments described here suggest that a further important factor is modulation of translation through changes in biogenesis and levels of miRNAs.

Keyphrases

induced apoptosis
reactive oxygen species
cell cycle arrest
cell death
dna damage
endoplasmic reticulum stress
radiation therapy