First non-invasive magnetic phrenic nerve and diaphragm stimulation in anaesthetized patients: a proof-of-concept study.

Alessandro PanelliHermann Georges BartelsSven KrauseMichael André VerfußAline Michèle GrimmNiklas Martin CarbonJulius J GrunowDiego StutzerThomas NiederhauserLaurent BrochardSteffen Weber-CarstensStefan J Schaller

Published in: Intensive care medicine experimental (2023)

Bilateral non-invasive electromagnetic phrenic nerve stimulation generated a tidal volume of 3-6 ml/kg ideal body weight due to diaphragmatic contraction in lung-healthy anaesthetized patients. Further perspectives in critically ill patients should include assessment of clinical outcomes to confirm whether diaphragm contraction through non-invasive electromagnetic phrenic nerve stimulation potentially ameliorates or prevents diaphragm atrophy.

Keyphrases

end stage renal disease
ejection fraction
body weight
chronic kidney disease
newly diagnosed
prognostic factors
high resolution
mass spectrometry
high frequency
smooth muscle