Clinical pharmacology of analgosedatives in neonates: ways to improve their safe and effective use.

Anne SmitsJohn N van den AnkerKarel Allegaert

Published in: The Journal of pharmacy and pharmacology (2016)

Product development programmes for analgosedatives in neonates are needed. These programmes should be tailored to their specific needs (short-acting sedation, pain relief), should include long-term safety and should incorporate the exploration of newer covariates like pharmacogenetics.

Keyphrases

low birth weight
chronic pain
pain management
neuropathic pain
preterm infants
preterm birth
spinal cord injury
extracorporeal membrane oxygenation