Serotonergic neurons are involved in the counter-regulatory response to hypoglycemia.
Hugo MartinAdeline CoursanJustine LallementMathieu Di MiceliJanany KandiahIlyès RahoJasmine ButtlerJean-Philippe GuillouxPhilippe De DeurwaerdereSophie LayéVanessa H RouthBruno P GuiardChristophe MagnanCéline Cruciani-GuglielmacciXavier FioramontiPublished in: Journal of neuroendocrinology (2023)
Taken together, these data highlight a new neuronal network involved in the regulation of the CRR. In particular, this study shows that DR 5-HT neurons detect iatrogenic hypoglycemia in response to the increased insulin level and may play an important role in the regulation of CRR.