A global screening identifies chromatin-enriched RNA-binding proteins and the transcriptional regulatory activity of QKI5 during monocytic differentiation.
Yue RenYue HuoWeiqian LiManman HeSiqi LiuJiabin YangHongmei ZhaoLingjie XuYuehong GuoYanmin SiHualu ZhaoShuan RaoJing WangYanni MaXiaoshuang WangJia YuFang WangPublished in: Genome biology (2021)
Our study indicates that Che-RBPs are versatile factors that orchestrate gene expression in different cellular contexts, and identifies QKI5, a classic RBP regulating RNA processing, as a novel transcriptional activator during monocytic differentiation.