Risk prediction of atrial fibrillation in the community combining biomarkers and genetics.
Christin S BörschelAmelie H OhlroggeBastiaan GeelhoedTeemu NiiranenAki S HavulinnaTarja PalosaariPekka JousilahtiMichiel RienstraPim van der HarstStefan BlankenbergTanja ZellerVeikko V SalomaaRenate B SchnabelPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2021)
The PRS and the established biomarker NT-proBNP showed comparable predictive ability. Both provided incremental predictive value over standard clinical variables. Further improvements for the PRS are likely with the discovery of additional SNPs.