Noninvasive ventilation vs. high-flow nasal cannula oxygen for preoxygenation before intubation in patients with obesity: a post hoc analysis of a randomized controlled trial.
Maeva RodriguezStéphanie RagotRémi CoudroyJean-Pierre QuenotPhilippe VignonJean-Marie ForelAlexandre DemouleJean-Paul MiraJean-Damien RicardSaad NseirGwenhael ColinBertrand PonsPierre-Eric DaninJérome DevaquetGwenael PratHamid MerdjiFranck PetitpasEmmanuel VivierArmand Mekontso-DessapMai-Anh NayPierre AsfarJean DellamonicaLaurent ArgaudStephan EhrmannMuriel FartoukhChristophe GiraultRené RobertArnaud W ThilleJean-Pierre Fratnull nullPublished in: Annals of intensive care (2021)
Patients with obesity and acute hypoxemic respiratory failure had an increased risk of severe hypoxemia during intubation procedure as compared to patients without obesity. However, preoxygenation with noninvasive ventilation may not reduce this risk compared with high-flow nasal oxygen. Trial registration Clinical trial number: NCT02668458 ( http://www.clinicaltrials.gov ).
Keyphrases
- respiratory failure
- extracorporeal membrane oxygenation
- insulin resistance
- mechanical ventilation
- clinical trial
- metabolic syndrome
- weight loss
- high fat diet induced
- type diabetes
- weight gain
- end stage renal disease
- cardiac arrest
- ejection fraction
- newly diagnosed
- study protocol
- phase ii
- acute respiratory distress syndrome
- chronic kidney disease
- early onset
- prognostic factors
- minimally invasive
- intensive care unit
- chronic rhinosinusitis
- physical activity
- body mass index
- skeletal muscle
- liver failure
- patient reported
- hepatitis b virus
- obstructive sleep apnea