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The gut microbiome and type 2 diabetes status in the Multiethnic Cohort.

Gertraud MaskarinecPhyllis RaquinioBruce S KristalVeronica W SetiawanLynne R WilkensAdrian A FrankeUnhee LimLoïc Le MarchandTimothy W RandolphJohanna W LampeMeredith A J Hullar
Published in: PloS one (2021)
T2D but not PT2D/UT2D status was associated with lower abundance of SCFA-producing genera and a higher abundance of gram-negative endotoxin-producing bacteria suggesting that the gut microbiome may contribute to chronic systemic inflammation and T2D through bacterial translocation.
Keyphrases
  • gram negative
  • multidrug resistant
  • type diabetes
  • antibiotic resistance genes
  • cardiovascular disease
  • glycemic control
  • insulin resistance
  • adipose tissue
  • weight loss