TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo .
Jinhee KimDeepanwita BoseMariluz AraíngaMuhammad R HaqueChristine M FennesseyRachel A CaddellYanique ThomasDouglas E FerrellSyed AliEmanuelle GrodyYogesh GoyalClaudia CicalaJames ArthosBrandon F KeeleMonica VaccariRamon Lorenzo-RedondoThomas J HopeFrancois VillingerElena MartinelliPublished in: bioRxiv : the preprint server for biology (2023)
TGF-β blockade drives an effector phenotype in immune cells leading to SIV latency reversal and enhanced immune responses in vivo.