Gene expression changes associated with malignant transformation of oral potentially malignant disorders.

Hans Prakash SathasivamJohn CasementTimothy BatesPhilip SloanPeter J Thomson Max Robinson Ralf Kist

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2020)

Several candidate genes that may play a role in malignant transformation of OPMD have been identified. Experiments to validate these candidates are underway. It is anticipated that this work will contribute to better understanding of the etiopathogenesis of OPMD and development of novel biomarkers.

Keyphrases

gene expression
dna methylation