Dose per muscle in cervical dystonia: pooled data from seven movement disorder centres.
Wolfgang H JostArtur DrużdżSanjay PandeyBo Biering-SørensenAlexandre KreislerLaurent TatuChristian F AltmannJarosław SławekPublished in: Neurologia i neurochirurgia polska (2021)
In clinical trials the doses per muscle are based on an arbitrary decision. In our study, the doses were lower than in other studies, which may be due to the number of muscles per session, the use of ultrasound guidance (and therefore more precise injections), as well as the use of the Col-Cap concept. Our results exemplify everyday practice, and may help as the basis for recommendations and further investigations.
Keyphrases
- clinical trial
- skeletal muscle
- healthcare
- primary care
- magnetic resonance imaging
- ultrasound guided
- early onset
- electronic health record
- deep brain stimulation
- big data
- computed tomography
- machine learning
- transcranial direct current stimulation
- decision making
- phase iii
- open label
- study protocol
- double blind
- placebo controlled