Reduced DNA methylation of the oxytocin receptor gene is associated with obsessive-compulsive disorder.

Chun Il ParkHae Won KimSumoa JeonJee In KangYoon-Keun Kim

Published in: Clinical epigenetics (2020)

Our findings suggest that epigenetic OXTR alterations may affect the pathophysiology of OCD. The potential role of the oxytocin system in OCD development and treatment warrants further investigation.

Keyphrases

obsessive compulsive disorder
dna methylation
genome wide
deep brain stimulation
gene expression
copy number
combination therapy
replacement therapy
climate change
transcription factor