Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders.

Friederike TullerHannah HolzerKathrin SchandaFahmy Aboulenein-DjamshidianRomana HöftbergerMichael KhalilThomas Seifert-HeldFritz LeutmezerThomas BergerMarkus Reindl

Published in: Journal of neuroinflammation (2016)

Our study demonstrates that AQP4-IgG in sera of NMOSD patients show distinct patterns of antibody recognition. The clinical and diagnostic relevance of these findings have to be addressed in prospective studies.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
systemic lupus erythematosus
prognostic factors
patient reported outcomes
binding protein
patient reported