Our study demonstrated that thymol could reduce the microglial inflammation by targeting PI3K/Akt/mTOR/NF-κB signaling pathway, ultimately alleviating ischemic brain injury. These findings suggest that thymol is a promising candidate as a neuroprotective agent against ischemic stroke.
Keyphrases
- cerebral ischemia
- brain injury
- signaling pathway
- subarachnoid hemorrhage
- lps induced
- pi k akt
- inflammatory response
- blood brain barrier
- oxidative stress
- neuropathic pain
- epithelial mesenchymal transition
- lipopolysaccharide induced
- induced apoptosis
- atrial fibrillation
- nuclear factor
- multiple sclerosis
- toll like receptor