Expansion of interferon signaling-associated gene (ISAG) hi T cells in early-onset Alzheimer's disease.
Daniel W SirkisCaroline Warly SolsbergTaylor P JohnsonEthan G GeierLuke W BonhamBruce L MillerGil D RabinoviciJennifer S YokoyamaPublished in: bioRxiv : the preprint server for biology (2023)
cells, which are primed for antiviral response, are expanded in early-but not late-onset AD or primary familial tauopathy, suggesting they may provide unique insight into the immune response to EOAD.