Statin-associated immune-mediated necrotizing myopathy: a retrospective analysis of individual case safety reports from VigiBase.

Dirk EssersMartina SchäublinGerd A Kullak-UblickStefan Weiler

Published in: European journal of clinical pharmacology (2018)

The number of IMNM reports has increased in recent years. IMNM associated with statin treatment seems to occur worldwide. Most IMNM cases were reported with atorvastatin. No dose dependency of statin-associated IMNM pathogenesis was identified.

Keyphrases

cardiovascular disease
coronary artery disease
low density lipoprotein
adverse drug
emergency department
combination therapy
muscular dystrophy