No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study.

Daniel M JordanHyon K ChoiMarie Verbanck Ruth Topless Hong-Hee Won Girish Nitin NadkarniTony R MerrimanRon Do

Published in: PLoS medicine (2019)

Evidence from our series of causal inference approaches using genetics does not support a causal effect of SU level on eGFR level or CKD risk. Reducing SU levels is unlikely to reduce the risk of CKD development.

Keyphrases

chronic kidney disease
end stage renal disease
small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
single cell