The anti-inflammatory and anti-apoptotic effects of Achillea millefolium L. extracts on Clostridioides difficile ribotype 001 in human intestinal epithelial cells.
Hamideh RaeisiMasoumeh AzimiradSamaneh Asadi-SanamHamid Asadzadeh AghdaeiAbbas YadegarMohammad Reza ZaliPublished in: BMC complementary medicine and therapies (2024)
The results of the present study for the first time demonstrate the antimicrobial activity and protective effects of A. millefolium extracts on inflammatory response and apoptosis induced by Tox-S from C. difficile RT001 clinical strain in vitro. Further research is needed to evaluate the potential application of A. millefolium extracts as supplementary medicine for CDI prevention and treatment in clinical setting.