Comparison of discovery rates and prognostic utility of [ 68 Ga]Ga-PSMA-11 PET/CT and circulating tumor DNA in prostate cancer-a cross-sectional study.

Kilian KlugeHolger EinspielerDavid HaberlClemens SpielvogelDominik AmerellerGerda EggerGero KramerBernhard GrubmüllerShahrokh ShariatMarcus HackerLukas KennerAlexander R Haug

Published in: European journal of nuclear medicine and molecular imaging (2024)

These findings suggest that PSMA PET imaging outperforms ctDNA analysis in detecting prostate cancer across the whole spectrum of disease, while both modalities are independently highly prognostic for survival outcomes.

Keyphrases

pet ct
circulating tumor
prostate cancer
pet imaging
positron emission tomography
radical prostatectomy
cell free
circulating tumor cells
small molecule
high throughput
single cell
data analysis