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Chronic neutrophilic leukemia: 2018 update on diagnosis, molecular genetics and management.

Michelle A ElliottAyalew Tefferi
Published in: American journal of hematology (2019)
Concurrent mutations, common to myeloid neoplasms and their precursor states, most frequently in SETBP1 and ASXL1, are frequent and appear to be of prognostic significance. Although data are evolving on the full genomic profile, the rarity of CNL has delayed complete understanding of its full molecular pathogenesis and individual patient prognosis.
Keyphrases
  • acute myeloid leukemia
  • bone marrow
  • dendritic cells
  • single molecule
  • case report
  • squamous cell carcinoma
  • machine learning
  • gene expression
  • rectal cancer