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Exercise improves surrogate measures of liver histological response in metabolic dysfunction-associated steatotic liver disease.

Daniel J CuthbertsonShelley Elizabeth KeatingChristopher J A PughPatrick J OwenGraham J KempA Margot UmplebyNathaniel G GeyerVernon M ChinchilliJonathan G Stine
Published in: Liver international : official journal of the International Association for the Study of the Liver (2024)
Exercise training led to clinically meaningful improvements in surrogate serum- and imaging-based measures of liver histological change, without clinically meaningful body weight reduction. These data reinforce the weight-neutral benefit of exercise training and suggest that aerobic training may improve liver fibrosis in patients with MASLD.
Keyphrases
  • body weight
  • liver fibrosis
  • high intensity
  • skeletal muscle
  • physical activity
  • high resolution
  • body mass index
  • electronic health record
  • oxidative stress
  • big data
  • data analysis