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Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells.

Showgy Y Ma'ayehJingyi LiuDimitra PeirasmakiKatarina HörnaeusSara Bergström LindManfred GrabherrJonas BergquistStaffan G Svärd
Published in: PLoS neglected tropical diseases (2017)
This is the first study identifying Giardia ESPs and evaluating their effects on IECs. It highlights the importance of host and parasite ESPs during interactions and reveals the intricate cellular responses that can explain disease mechanisms and attenuated inflammatory responses during giardiasis.
Keyphrases
  • induced apoptosis
  • endothelial cells
  • cell cycle arrest
  • induced pluripotent stem cells
  • oxidative stress
  • toxoplasma gondii
  • cell proliferation