Photo-induced 1,2-thiohydroxylation of maleimide involving disulfide and singlet oxygen.

Tamanna Khandelia Subhendu Ghosh Pritishree Panigrahi Raju Mandal Deepjyoti Boruah Bhisma K Patel

Published in: Chemical communications (Cambridge, England) (2023)

A visible light-driven di-functionalization of maleimide with disulfide and in situ -generated singlet oxygen offers selective 1,2-thiohydroxylation under additive-free conditions. Here the disulfide plays the dual role of photosensitizer and the coupling reagent. Notably, the hydroxyl functionality originates from the in situ generated singlet oxygen followed by HAT from H 2 O (moisture).

Keyphrases

visible light
photodynamic therapy
energy transfer
high glucose
diabetic rats
room temperature
drug induced
biofilm formation
ionic liquid