Ethanol consumption and sedation are altered in mice lacking the glycine receptor α2 subunit.

Loreto San MartinScarlet GallegosAnibal ArayaNicol RomeroGiovanni MorelliJoris ComhairRobert J Harvey Jean-Michel Rigo Bert Brône Luis G Aguayo

Published in: British journal of pharmacology (2020)

The differences in ethanol consumption between WT and KO mice provide additional evidence supporting the conclusion that GlyRs are biologically relevant targets for the sedative and rewarding properties of ethanol.

Keyphrases

high fat diet induced
insulin resistance
intensive care unit
metabolic syndrome
binding protein
skeletal muscle