Drosophila ClC-c is a Homolog of Human CLC-5 and a New Model for Dent Disease Type 1.

Carmen J Reynolds Christopher M Gillen Richard Burke Yula TseringEmi LoucksSebastian Judd-Mole Julian A T Dow Michael F Romero

Published in: Kidney360 (2024)

Drosophila ClC-c shows orthologous function and localization to human ClC-5. Thus, Drosophila and ClC-c regulation may be useful for future investigations of Cl- transport, Ca2+ homeostasis and urinary protein loss in DD1.

Keyphrases

endothelial cells
induced pluripotent stem cells
current status
binding protein