A novel near-infrared fluorescent probe for the imaging of viscosity in cells and tumor-bearing mice.
Qin-Ting LiaoJing-Jing ChaoWen-Xin WangTing LiuGuo-Jiang MaoFen XuChun-Yan LiPublished in: Chemical communications (Cambridge, England) (2023)
A near-infrared fluorescent probe (IC-V) for detecting viscosity is constructed. The probe has a large Stokes shift (170 nm) and an about 180-fold increase in fluorescence intensity at 700 nm. In addition, IC-V can not only distinguish cancer cells from normal cells, but also monitor viscosity in normal mice and tumor-bearing mice.
Keyphrases
- fluorescent probe
- living cells
- induced apoptosis
- high fat diet induced
- cell cycle arrest
- single molecule
- high resolution
- photodynamic therapy
- cell death
- signaling pathway
- papillary thyroid
- endoplasmic reticulum stress
- squamous cell carcinoma
- type diabetes
- quantum dots
- fluorescence imaging
- lymph node metastasis
- squamous cell
- insulin resistance