Acute Toxicity of a Marine Emerging Pollutant (Promethazine Hydrochloride) on Artemia sp.
Sara IgnotoRoberta PecoraroElena Maria ScalisiSharon Esmeralda ButtigèMartina ContinoGreta FerruggiaAntonio SalvaggioMaria Violetta BrundoPublished in: ACS omega (2022)
Recently, there has been a worrying increase in the pollution of the aquatic ecosystem caused by emerging contaminants (ECs) detected in wastewater effluent discharges. Although traces of ECs in waters have been found in low concentrations, it leads to negative effects for nontarget organisms. Antihistamines are a class of drugs largely used, whose metabolites are widespread in the aquatic ecosystem. The aim of the study was to evaluate the short-term effects of promethazine hydrochloride on nauplii of Artemia sp. A high percentage of mortality and morphological alterations were found. The results suggest a possible correlation between exposure to antihistamine and an acceleration of larval development.
Keyphrases
- risk assessment
- human health
- climate change
- wastewater treatment
- heavy metals
- liver failure
- ms ms
- anaerobic digestion
- cardiovascular events
- oxidative stress
- drug induced
- respiratory failure
- particulate matter
- cardiovascular disease
- risk factors
- health risk assessment
- aortic dissection
- coronary artery disease
- multidrug resistant
- gram negative
- aedes aegypti
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- mechanical ventilation