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MicroRNA regulatory networks associated with abnormal muscle repair in survivors of critical illness.

Christopher J WalshCarlos Escudero KingMuskan GuptaPamela J PlantMargaret J HerridgeSunita MathurPingzhao HuJudy CorreaSameen AhmedAnne BigotClaudia C Dos SantosJane Battnull null
Published in: Journal of cachexia, sarcopenia and muscle (2022)
Combined functional transcriptomics identified 36 miRs including miRs-424-3p/5p, -490-3p, and -744-5p as potential regulators of gene networks associated with recovery of muscle mass and strength following critical illness. MiR-490-3p is identified as a novel regulator of myogenesis.
Keyphrases
  • transcription factor
  • single cell
  • genome wide identification
  • skeletal muscle
  • young adults
  • genome wide
  • copy number
  • human health
  • dna methylation
  • climate change