Clinicopathological Features of Triple-Negative Breast Cancer Epigenetic Subtypes.

Maggie L DiNomeJavier I J OrozcoChikako MatsubaAyla O Manughian-PeterMiquel Ensenyat-MendezShu-Ching ChangJohn R JalasMatthew P SalomonDiego M Marzese

Published in: Annals of surgical oncology (2019)

TNBC epigenetic subtypes exhibit significant clinical and molecular differences. The links between genetic make-up, gene expression programs, and epigenetic subtypes open new avenues in the development of laboratory tests to more efficiently stratify TNBC patients, helping optimize tailored treatment approaches.

Keyphrases

gene expression
dna methylation
end stage renal disease
genome wide
ejection fraction
chronic kidney disease
peritoneal dialysis
patient reported outcomes
copy number
single molecule
combination therapy
replacement therapy