Clinical Guideline for Preimplantation Genetic Testing in Inherited Cardiac Diseases.
Job A J VerdonschotVanessa P M van EmpelVanessa P M van EmpelMalou HeijligersSonja de MunnikEdith CoonenJos C M F DreesenArthur van den WijngaardHan G BrunnerMasoud Zamani EstekiStephane R B HeymansChristine E M De Die-SmuldersAimée D C PaulussenPublished in: Circulation. Genomic and precision medicine (2024)
The number of PGT requests for inherited cardiac diseases increases rapidly, without the availability of specific guidelines. We propose a 2-step decision model that helps select couples with the highest risk reduction for cardiac disease in their offspring after PGT.