Cerebrospinal Fluid Pathologies in Schizophrenia-Spectrum Disorder-A Retrospective Chart Review.
Mattia CampanaJohanna StraußSusanne MünzTatiana Oviedo-SalcedoPiyumi FernandoPeter EichhornPeter FalkaiAlkomiet HasanElias WagnerPublished in: Schizophrenia bulletin (2021)
This large retrospective analysis on FEP cohort greatly enriches the clinical data available on this population and contributes to the discussion around inflammation in psychosis. Of note, even though several inflammatory alterations were found both in CSF and in blood tests, we found no evidence for a significant relationship between peripheral inflammation and inflammatory CSF. Furthermore, no significant relationship between CSF alterations and peripheral inflammation measured with CRP could be established.