Outcomes following oropharyngeal squamous cell carcinoma resection and bilateral neck dissection with or without contralateral postoperative radiotherapy of the pathologically node-negative neck.

Florian JansenChristian Stephan BetzMatthias Hans BelauGesa MatnjaniTill Sebastian ClauditzSebastian Dwertmann-RicoKatharina StölzelNikolaus MöckelmannArne Böttcher

Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2023)

Omitting the contralateral pathologically node-negative neck appears to be safe in terms of survival and our retrospective study advocates further prospective randomized control de-escalation trials.

Keyphrases

squamous cell carcinoma
open label
lymph node
early stage
locally advanced
double blind
clinical trial
patients undergoing
phase iii
rectal cancer