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Clinical actionability of genetic findings in cerebral palsy.

Sara A LewisMaya ChopraJulie S CohenJennifer M BainBhooma R AravamuthanJason B CarmelMichael Collingwood FaheyReeval SegelRichard F WintleMichael ZechHalie J MayNahla HaqueDarcy L FehlingsSiddharth SrivastavaMichael C Kruer
Published in: medRxiv : the preprint server for health sciences (2023)
of these genetic findings. Thus, genetic sequencing to identify these individuals for precision medicine interventions could improve outcomes and provide clinical benefit to individuals with CP. The relatively limited evidence base for most interventions underscores the need for additional research.
Keyphrases
  • cerebral palsy
  • genome wide
  • physical activity
  • copy number
  • single cell
  • dna methylation
  • adipose tissue
  • skeletal muscle
  • insulin resistance