Neoadjuvant Chemotherapy in Breast Cancer: Evaluation of the Impact on Surgical Outcomes and Prognosis.
Corrado ChiappaMaltecca GretaLeoni MiriamGiuseppe IettoDavide InversiniAndrea BallabioAlice BonettiAlberto ManganoRossana GueliGiulio CarcanoFrancesca Angela RoveraPublished in: Cancers (2024)
The correlation between TNM staging and histology variations in a sample of patients who underwent neoadjuvant chemotherapy demonstrates a positive impact on both increasing conservative surgery and achieving pCR, resulting in better outcomes in terms of disease-free survival (DFS) and the risk of relapse. Benefits have also been highlighted in terms of cosmetic outcomes, postoperative complications, and psychological benefits. However, the overall outcomes must be evaluated according to the subtype and individual characteristics of the patients.
Keyphrases
- neoadjuvant chemotherapy
- end stage renal disease
- free survival
- lymph node
- ejection fraction
- locally advanced
- newly diagnosed
- sentinel lymph node
- minimally invasive
- peritoneal dialysis
- type diabetes
- early stage
- depressive symptoms
- young adults
- adipose tissue
- skeletal muscle
- physical activity
- acute coronary syndrome
- atrial fibrillation
- weight loss
- patient reported
- sleep quality