MicroRNA-126 Inhibit Viability of Colorectal Cancer Cell by Repressing mTOR Induced Apoptosis and Autophagy.

Li WeiZhanhong ChenNa ChengXing LiJie ChenDonghao WuMin DongXiangyuan Wu

Published in: OncoTargets and therapy (2020)

Our study demonstrated that miR-126-induced can regulate the activity of CRC cells via autophagy and apoptosis and suggested a new mechanism of miR-126-mTOR interaction in CRC pathogenesis.

Keyphrases

induced apoptosis
endoplasmic reticulum stress
cell proliferation
oxidative stress
signaling pathway
long non coding rna
diabetic rats
long noncoding rna
cell death
cell cycle arrest
pi k akt
high glucose
cell therapy
stem cells