Genetic risk score (GRS) constructed from polymorphisms in the PON1, IL-6, ITGB3, and ALDH2 genes is associated with the risk of coronary artery disease in Pakistani subjects.

Shabana N ASana AshiqAnam IjazFizah KhalidIstabsar Ul SaadatKahkashan KhanSumbal SarwarSaleem Ullah Shahid

Published in: Lipids in health and disease (2018)

In conclusion, use of a GRS can provide better information than individual SNPs. The larger the number of the SNPs included in the analysis, the better would be the risk prediction.

Keyphrases

genome wide
coronary artery disease
dna methylation
copy number
wastewater treatment
percutaneous coronary intervention
coronary artery bypass grafting
genome wide association
heart failure
type diabetes
acute coronary syndrome
aortic valve
bioinformatics analysis