Cardiovascular adverse events-related to GnRH agonists and GnRH antagonists: analysis of real-life data from Eudra-Vigilance and Food and Drug Administration databases entries.

Antonio CicioneAntonio NacchiaAlessandro GuercioCarmen GravinaAntonio FrancoMaria Chiara GrimaldiGiorgia TemaRiccardo LombardoAndrea TubaroCosimo De Nunzio

Published in: Prostate cancer and prostatic diseases (2023)

Real-life data are consistent with registry studies regarding side effects related to HT. Real-life data suggest GnRH agonists are associated with higher CV AEs when compared to GnRH antagonists. Clinicians should consider these data when prescribing HT especially in patients with CV comorbidities.

Keyphrases

electronic health record
big data
drug administration
emergency department
palliative care
machine learning