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Degradation of magnetic nanoparticles mimicking lysosomal conditions followed by AC susceptibility.

Lucia GutiérrezSonia RomeroGustavo B da SilvaRocío CostoMaria D VargasCélia M RonconiCarlos J SernaSabino Veintemillas-VerdaguerMaría Del Puerto Morales
Published in: Biomedizinische Technik. Biomedical engineering (2016)
A model for the in vivo degradation of magnetic nanoparticles has been followed to gain insight on the changes of the magnetic properties of iron oxides during their degradation. The degradation kinetics is affected by the particle coating, in our case being the phosphonoacetic acid-coated particles degraded faster than the citric acid-coated ones.
Keyphrases
  • magnetic nanoparticles
  • mass spectrometry
  • high resolution
  • simultaneous determination