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The in vitro gastrointestinal digestion-associated protein corona of polystyrene nano- and microplastics increases their uptake by human THP-1-derived macrophages.

Hugo BrouwerMojtaba PorbahaieSjef BoerenMathias BuschHans Bouwmeester
Published in: Particle and fibre toxicology (2024)
This study provides quantitative data on the presence of gastrointestinal proteins on MNPs and relates this to cellular uptake, underpinning the need to include the protein corona in hazard assessment of MNPs.
Keyphrases
  • endothelial cells
  • electronic health record
  • high resolution
  • induced pluripotent stem cells
  • protein protein
  • small molecule
  • amino acid
  • binding protein
  • data analysis