Detection of MET gene somatic mutations in hepatocellular carcinoma of Egyptian patients using next-generation sequencing.

Ehab AhmedNour El-DienSalwa SabetMohamed KhalifaManal El Hamshary

Published in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2023)

Screening of the targeted genes such as c-MET for potential mutations is very important in the determination of the appropriate therapy. Therefore, it can be used as a biomarker in the prognosis of HCC. Such screenings are also of paramount importance in the development of personalized medicine.

Keyphrases

copy number
end stage renal disease
genome wide
newly diagnosed
tyrosine kinase
chronic kidney disease
prognostic factors
genome wide identification
stem cells
gene expression
bone marrow
risk assessment
climate change
molecularly imprinted
circulating tumor cells