Early emergence of sexual dimorphism in offspring leukocyte telomere length was associated with maternal and children's glucose metabolism-a longitudinal study.

Kwun Kiu Wong Feifei Cheng Cadmon K P Lim Claudia Ha-Ting Tam Greg E Tutino Connie Lai Yuk Yuen Chi Chiu Wang Yong Hou Michael Ho Ming Chan Chung Shun Ho Mugdha V Joglekar Anandwardhan A Hardikar Andrzej S Januszewski Boyd E Metzger William L Lowe Wing-Hung Tam Ronald Ching-Wan Ma

Published in: BMC medicine (2022)

Our findings suggest a close association between maternal and offspring glucose metabolic traits with early life LTL, with the offspring sex as an important modifier of the disparate relationships in insulin production and response.

Keyphrases

early life
high fat diet
birth weight
type diabetes
pregnancy outcomes
young adults
mental health
genome wide
physical activity
peripheral blood
gene expression
blood pressure
gestational age
weight loss