Deciphering the TLR transcriptome and downstream signaling pathway in cerebrospinal fluid in pediatric meningitis.
Manila SalariaSunit SinghiPratibha SinghiMadhulika SharmaNavdeep MangatTanvi BhatiaRonny WickstromRitu AggarwalPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2022)
Our findings provide support for future studies exploring TLR-based adjunct therapy to limit the neurological sequelae, owing to persistent inflammation in pediatric ABM patients.
Keyphrases
- cerebrospinal fluid
- signaling pathway
- end stage renal disease
- toll like receptor
- inflammatory response
- immune response
- ejection fraction
- chronic kidney disease
- newly diagnosed
- oxidative stress
- prognostic factors
- gene expression
- genome wide
- single cell
- stem cells
- rna seq
- dna methylation
- nuclear factor
- brain injury
- bone marrow
- subarachnoid hemorrhage
- smoking cessation
- case control