Concordance of ALK fusion gene-rearrangement between immunohistochemistry and next-generation sequencing.

Kazushige WakudaMeiko MoritaMotoki SekikawaNoboru MorikawaKeita MiuraKosei DoshitaYuko IidaHiroaki KodamaNobuaki MamesayaHaruki KobayashiRyo KoAkira OnoHirotsugu KenmotsuTateaki NaitoHaruyasu MurakamiKoji MuramatsuTakuya KawataKeita MoriTetsuo ShimizuYasuhiro GonToshiaki Takahashi

Published in: International journal of clinical oncology (2024)

Our results suggest that IHC and NGS might be complementary tests. In patients suspected of harboring ALK fusion gene-rearrangement, it should be analyzed using another diagnostic method.

Keyphrases

copy number
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
genome wide
advanced non small cell lung cancer
prognostic factors
pulmonary embolism
gene expression
dna methylation